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One school of scholars suggest that any birth sex ratio of boys to girls that is outside of the normal 105-107 range, necessarily implies sex-selective abortion.

Sen pointed to research that had shown that if men and women receive similar nutritional and medical attention and good health care then females have better survival rates, and it is the male which is the genetically fragile sex.

Sen estimated 'missing women' from extra women who would have survived in Asia if it had the same ratio of women to men as Europe and United States.

According to Sen, the high birth sex ratio over decades, implies a female shortfall of 11% in Asia, or over 100 million women as missing from the 3 billion combined population of South Asia, West Asia, North Africa and China.

Sex-selective abortion is the practice of terminating a pregnancy based upon the predicted sex of the infant.

The selective abortion of female fetuses is most common in areas where cultural norms value male children over female children, especially in parts of East Asia and South Asia (particularly in countries such as People's Republic of China, India and Pakistan), as well as in the Caucasus, and Southeast Europe.

Studies and reports focusing on sex-selective abortion are predominantly statistical; they assume that birth sex ratio—the overall ratio of boys and girls at birth for a regional population, is an indicator of sex-selective abortion.This assumption has been questioned by some scholars.Countries considered to have significant practices of sex-selective abortion are those with birth sex ratios of 108 and above (selective abortion of females), and 102 and below (selective abortion of males).Studies and reports that discuss sex-selective abortion are based on the assumption that birth sex ratio—the overall ratio of boys and girls at birth for a regional population, is an indicator of sex-selective abortion.Human sex ratio at birth that is significantly different from 106 is often assumed to be correlated to the prevalence and scale of sex-selective abortion.This assumption is controversial, and a subject of continuing scientific studies.

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